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53 Generally, the reported K m of PARP1 and CD38 for NAD + are lower than those of the sirtuins, suggesting that elevated activation of PARP1 or CD38 may limit endogenous SIRT activation by reducing NAD + content

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Extracellular matrix

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The cartridge is suspended inside a chamber filled with a bicarbonate-based buffer to simulate the interstitial fluid

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There is nothing to detect

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